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Perimenopause

Perimenopause is the process of change leading up to menopause, which is the point in your life when you stop having periods. It can start as early as your late 30s or as late as your early 50s.

How long perimenopause lasts varies by the person, but it typically ranges from two to eight years.

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What Is Perimenopause?

Perimenopause is the hormonal transition leading up to menopause, which is the point in your life when you stop having periods for 12 months (or immediately following the surgical removal of both ovaries). Perimenopause may begin as early as in your late 30s or as late as in your early 50s.

As you approach menopause, your body begins to produce less estrogen and progesterone. These hormonal changes can affect your mood and cause irregular periods and physical symptoms.

What causes perimenopause?

Perimenopause is a natural part of aging. It occurs due to the declining number of eggs available in the ovaries, which produce hormones needed for menstrual periods and pregnancies.

What is the difference between perimenopause and menopause?

When people talk about menopause, they're often really referring to perimenopause. 

Menopause is the cessation (stopping) of your period. When a person hasn't had a period for 12 months, they're considered menopausal. They are also considered menopausal immediately after both ovaries are surgically removed, regardless of how young they are.

Perimenopausal women may have irregular periods but are still able to get pregnant. During perimenopause, you should continue to use protection during sexual intercourse to prevent unwanted pregnancies.

What is premature menopause?

About 1% of U.S. women are considered to have premature menopause, meaning they experience menopause before age 40. Premature menopause can be the result of genetic, metabolic, or autoimmune conditions. It also occurs with the surgical removal of both ovaries.

The symptoms of premature menopause are similar to those of perimenopause. Because people with premature menopause spend less time without the benefits of estrogen production, they're at greater risk for health problems like osteoporosis, heart disease, and dementia.

How long does perimenopause last?

Perimenopause typically lasts two to eight years, and ends when a person hasn't had a period for 12 months. At that point, they have reached menopause.

For some women, the onset of perimenopause can occur in their 30s, but for most people, it happens in their 40s or 50s.

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What Are the Symptoms of Perimenopause?

There are many symptoms of perimenopause. How severe these symptoms are and how long they last will vary by person.

Menopausal symptoms are thought to be a result of changing hormone levels, which is why they may be unpredictable and vary in severity.

Many people undergoing the menopausal transition will experience genitourinary syndrome of menopause, or GMS. This condition involves changes to the vulva, vagina, urethra, and bladder. People with GMS may experience vaginal dryness, pain during sex, urinary urgency, or bladder infections.

How do you know if you are in perimenopause?

If you're approaching your 40s or 50s and notice irregularities in your period, you may be experiencing perimenopause. 

Irregularities may include periods that:

  • Have more or less bleeding than usual.
  • Last longer or are shorter than usual.
  • Occur very close together or at unexpected times.
  • Resume after no bleeding for more than a month but less than a year.

Other common perimenopause experiences include:

  • Aches and pains in muscles and joints.
  • Loss of bladder control (incontinence) — You may suddenly need to urinate or leak during exercise, sneezing, or laughing. 
  • Bladder infections.
  • Cognitive changes – You may experience forgetfulness, slower thinking, confusion, and difficulty concentrating.
  • Decreased sex drive – You may have shifting feelings about or loss of interest in sex.
  • Difficulty sleeping – You may have trouble falling asleep or staying asleep.
  • Dry skin – Aging skin retains less moisture, resulting in dryness. It also loses structural proteins called collagen and elasticity, creating sags or wrinkles.
  • Headaches.
  • Heart palpitations.
  • Hot flashes – A sudden feeling of heat in your body may cause flushing of the face and neck, red blotches, heavy sweating, and cold shivering. Hot flashes can last between 30 seconds and 10 minutes.
  • Mood disturbances – You may feel moodier, more anxious, or more irritable.
  • Night sweats – Hot flashes that wake you from your sleep.
  • Vaginal itching or dryness.
  • Pain during intercourse (dyspareunia) – Vaginal dryness may make sex uncomfortable or painful.
  • Weight gain – You may notice more abdominal fat due to muscle and body composition changes.

The menopausal transition also may result in a range of mental health problems. Women with a history of clinical depression, premenstrual syndrome (PMS), or postpartum depression are at a higher risk of experiencing depressive symptoms during perimenopause. 

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When should I see a doctor about my perimenopause symptoms?

If you're between the ages of 30 and 50 and having symptoms of perimenopause, consider discussing them with your health care provider, especially if your symptoms are bothersome or your periods stopped before age 45.

Call your doctor right away if you're experiencing any of these symptoms consistently:

  • An increase in your use of drugs or alcohol.
  • A loss of interest in everyday activities.
  • A marked increase or decrease in your appetite and weight.
  • Changes in sleep patterns (difficulty falling asleep or staying asleep, early morning awakening, sleeping more than usual).
  • Decreased sense of well-being.
  • Depression that does not go away.
  • Difficulty thinking about anything other than aging or perimenopause symptoms.
  • High levels of anxiety, stress, or worry.
  • Inability to focus on completing tasks and difficulty concentrating.
  • Persistent feelings of pessimism, guilt, worthlessness, bitterness, or anger.
  • Social isolation.
  • Strain in your personal relationships.
  • Thoughts of death or suicide.

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How Do You Diagnose Perimenopause?

To determine if you're in perimenopause, your doctor will assess factors such as your age, menstrual pattern, symptoms, and family history.

Menopause is diagnosed after you have had no periods for 12 months or if you have had both ovaries surgically removed at any age.

Tests to diagnose perimenopause

If your health care provider suspects you are experiencing perimenopause and is unable to monitor your periods (due to prior hysterectomy, endometrial ablation, or use of hormonal IUD), they may order a blood test to check your follicle-stimulating hormone (FSH). FSH levels are high during menopause but fluctuate up and down during perimenopause.

While this test does not ensure a diagnosis, it may raise suspicion that you actually are in menopause if the FSH level is high.

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How Do You Treat Perimenopause?

You don't need treatment for perimenopause unless your symptoms bother you. Symptoms that are severe and affect your quality of life should improve with treatment.

Lifestyle changes for perimenopause

Making changes to your lifestyle may help you alleviate the symptoms of perimenopause without the need for medical intervention. 

You can often ease mild symptoms of perimenopause with lifestyle changes and adaptations, such as wearing light layers and carrying a portable fan.

Other things you can do to take care of yourself during perimenopause include:

  • Be proactive about your mental and emotional condition. Seek help at the first signs of problems or changes to your mental health.
  • Be sure you're getting enough calcium and vitamin D to help your bones stay strong. Eat foods that are rich in calcium. Ask your doctor if taking a calcium or vitamin D supplement is right for you.
  • Eat a heart-healthy diet. Choose unprocessed, whole foods such as vegetables, fruits, nuts, beans, fish, and whole grains. Limit foods that have a lot of salt, fat, and sugar.
  • Exercise regularly. Exercise helps manage your weight, keeps your heart and bones strong, may improve sleep, and lifts your mood.
  • If you smoke, stop. Quitting smoking can reduce hot flashes and long-term health risks.
  • Limit caffeine and alcohol.
  • Manage stress. Breathing exercises, meditation, or yoga may help. It is also helpful to give yourself time during the day to relax and do activities you enjoy.

Medicine for perimenopause

Perimenopausal symptoms can be alleviated and treated through the use of hormone therapy.

Some people prefer not to use hormone therapy. In this case, non-hormonal medicines can be prescribed. If you're interested in pursuing non-hormonal treatments, you should speak with your provider about your options.

Hormone therapy

Lower levels of hormones may lead to intense symptoms of perimenopause. Many people find relief in menopausal hormone therapy (MHT). Often, they're prescribed estrogen with or without a progesterone/progestin.

MHT should be used at the lowest effective dose and for the shortest duration needed.

Hormone therapy can help relieve:

  • Hot flashes.
  • Night sweats.
  • Pain during sex.
  • Vaginal dryness.

MHT also may reduce your chances of developing osteoporosis — a condition in which bones become thin and weak and may break more easily.

Hormone therapy may not be appropriate for perimenopausal women who might be pregnant or have problems with vaginal bleeding, certain cancers, or liver disease, or have a history of heart attack, stroke, or blood clots.

As with all medical interventions, there are some risks associated with MHT. These include stroke, blood clots, heart attacks, breast cancer, gallbladder disease, and endometrial cancer. Smoking while using MHT can further increase your risk.

Mental health concerns during perimenopause

Anyone experiencing perimenopause can develop related emotional, behavioral, and cognitive issues. However, if you have a personal or family history of mental health conditions, you may be at a higher risk of developing a mental health problem related to perimenopause.

You may also be at a higher risk for mental health issues during perimenopause if you have:

  • Concerns about menopause or aging.
  • High levels of stress.
  • Lack of support from other people in your life.
  • Low self-esteem.

The best way to prevent mental health issues is to be proactive about your mental and emotional condition and get help at the first sign of problems.

Treatment for anxiety, depression, perceived cognitive decline, stress, and other perimenopause-related mental health concerns depends on their specific cause, your symptoms, and the severity of your condition. 

Your doctor may recommend one or more treatments to improve your mental health during perimenopause.

Lifestyle changes for mental health during perimenopause

Lifestyle changes you can make to improve your mental health during perimenopause include:

  • Avoiding caffeine and alcohol.
  • Eating a healthy diet.
  • Exercising regularly.
  • Reserving time during the day to relax and spending time doing activities you enjoy.
  • Trying deep breathing, yoga, massage, or guided imagery to promote mental wellness. 

Medicines to help perimenopause mental health concerns

Antidepressant and anti-anxiety medications may be prescribed to treat moderate to severe psychiatric symptoms.

Before prescribing medication, your doctor will consider how the medication may interact with other medicines you're taking. UPMC psychiatrists will work closely with you and your ob-gyn to determine the safest and most effective mental health treatment.

Counseling during perimenopause

UPMC offers one-on-one counseling and group therapy to help women discuss and manage stress, depression, anxiety, and mood disorders. Our specialists may also recommend exercise therapy, light therapy, or other alternative options to help you manage your mental health condition during perimenopause.


Last reviewed by a UPMC medical professional on 2024-09-05.