Leuprolide Acetate (Generic Name)

Other Names: Eligard®, Lupron®, leuprorelin acetate

 

About this drug

Leuprolide acetate is used to treat some types of cancer and other health problems. This drug is given in a shot under the skin (SQ) or into a muscle (IM).

 

Possible side effects (more common)

  • Feeling flushed (“hot flashes”). This is often temporary.
  • Sweating more than normal
  • Bone pain
  • Feeling weak. This is often temporary.
  • Numbness, tingling, or decreased feeling in legs, feet, or toes. This is often temporary.
  • Sore or tender breasts
  • Loss of menstrual period in women
  • Nausea
  • Injection site pain
  • Headache

Possible side effects (less common)

  • Swelling of hands, ankles, or feet
  • Feeling dizzy
  • Pain when passing urine or trouble passing urine (rare)
  • Breast enlargement in men (rare)
  • In men it may change your ability to have sexual relations (rare).

Treating side effects

Ask your doctor or nurse about medicines that are available to help stop or lessen bone pain and nausea.

 

Food and drug interactions

There are no known interactions of leuprolide acetate with food. This drug may interact with other medicines. Tell your doctor and pharmacist about all the medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. The safety and use of dietary supplements and alternative diets are often not known. Using these might affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's help.

 

When to call the doctor

Call your doctor or nurse as soon as possible if you have any of these symptoms:

  • Swelling of hands, ankles, or feet
  • Bone pain that is not relieved by prescribed medicine
  • Nausea that is not relieved by prescribed medicine
  • Numbness, tingling, or decreased feeling in fingers and toes
  • Trouble walking or changes in the way you walk
  • Feeling clumsy when buttoning clothes, opening jars, or other routine hand activities
  • Pain when you pass urine or trouble passing urine
  • Sexual problems
  • Bad hot flashes or night sweats

Reproduction concerns

  • Pregnancy warning:  This drug may have harmful effects on the unborn child, so effective methods of birth control should be used during your cancer treatment. Talk with your doctor or nurse about effective methods of birth control.
  • Breast feeding warning:  Women should not breast feed during treatment because this drug could enter the breast milk and badly harm a breast feeding baby.

Revised July 2014

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