Fluoxymesterone (Generic Name)

Other Names: HalotestinĀ®, Ora-Testryl

About This Drug

Fluoxymesterone is used to treat cancer. This drug is given by mouth.

Possible Side Effects

  • Allergic reactions to this drug are rare, but may occur in some patients. Signs of allergic reaction are shortness of breath, rash or itching, dizziness or lightheadedness, or palpitations (feeling your heart beat rapidly).
  • Nausea
  • Patchy hair loss. Usually hair loss is temporary; your hair should grow back when treatment is completed.
  • Acne
  • Some females may experience increased facial hair, increase in size of the clitoris, increased sexual drive, and voice deepening.
  • Some males may experience excessive development of the breasts and excessive frequency and duration of penile erections.
  • Effects on the heart. High doses of this drug may weaken the heart and decrease heart function. Your heart function will be checked as needed.
  • Swelling of feet, face, arms, or trunk
  • Headache
  • Confusion
  • Anxiety
  • Generalized sensation of prickling, tingling, or creeping on the skin
  • Depression
  • Changes in liver enzymes. Liver enzymes will be checked as needed.
  • Sexual problems and reproduction concerns may occur. In men and women both, this drug may temporarily or permanently affect your ability to have children. This cannot be determined before your therapy. In men, this drug may interfere with your ability to make sperm, but it should not change your ability to have sexual relations. In women, menstrual bleeding may become irregular or stop while you are receiving this drug. Do not assume that you cannot become pregnant if you do not have a menstrual period. Women may experience signs of menopause, like vaginal dryness or itching.
      • This drug may have harmful effects on the unborn child, so effective methods of birth control should be used during your cancer treatment.
      • Genetic counseling is available to you to discuss the effect of this drug therapy on future pregnancies. In addition, a genetic counselor can review the potential risks of problems in the fetus due to this medication if an exposure during pregnancy has occurred.

Treating Side Effects

  • Ask your doctor or nurse about medication to help prevent or lessen nausea.
  • Talk to your doctor or nurse about obtaining a wig before you experience hair loss.
  • Use effective methods of birth control during your cancer treatment.
  • Speak with your doctor or nurse if you plan to have children. Ask for information on sperm or egg banking.
  • Talk with your doctor or nurse if you feel you need help with moods, such as anxiety or depression.
  • Talk with your doctor about treatment for acne and increase in facial hair.

Food and Drug Interactions

There are no known interactions of fluoxymesterone and any food. This drug may interact with other medications. Tell your doctor and pharmacist all the medications that you are currently taking.

When to Call the Doctor

Call your doctor or nurse immediately if you have any of the following symptoms:

  • Difficulty catching your breath
  • Rash or itching, dizziness or lightheadedness, or palpitations
  • Uncontrolled nausea that prevents you from eating or drinking
  • Confusion
  • Swelling of feet, face, arms, or trunk

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Call your doctor or nurse as soon as possible if you have any of the following symptoms:

  • Nausea unrelieved by prescribed medication
  • Headache unrelieved by prescribed medication
  • Yellowing of the skin or eyes
  • Sensation of prickling, tingling, or creeping on the skin
  • Clitoral enlargement
  • Sexual dysfunction
  • Acne
  • Increase in facial hair
  • Deepening of voice in females
  • Excessive development of the breasts in males
  • Excessive frequency and duration of penile erections
  • Changes in menstrual cycle

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