Dr. Barlett specializes in regional therapeutics – the delivery of chemotherapy or biological therapeutic agents directly to the blood vessels leading to a tumor.
Prior to joining University of Pittsburgh Cancer Institute (UPCI), Dr. Bartlett was a senior investigator in the surgery branch at the Center for Cancer Research at the National Cancer Institute where he performed isolated limb perfusion for the treatment of melanoma and developed innovative surgical techniques to deliver cancer treatment that resulted in improved survival and quality of life for patients with abdominal and liver cancers.
In addition to his work on regional therapeutics, Dr. Bartlett is investigating tumor directed gene therapy for cancer. He is currently working with the vaccinia virus (smallpox vaccine virus), using it as a vector to deliver gene therapy directly to tumor sites, and genetically engineering the virus to kill cancer cells.
Dr. Bartlett received his medical degree from the University of Texas Medical School at Houston and completed his surgical training at the Hospital of the University of Pennsylvania in Philadelphia. He also completed a fellowship in surgical oncology at Memorial Sloan-Kettering Cancer Center in New York.
Among his accomplishments, Dr. Bartlett has authored numerous articles on regional treatment strategies and tumor directed gene therapy in peer-reviewed journals such as Cancer Research and the Journal of the National Cancer Institute. He has also authored several chapters in textbooks on cancer therapeutics and surgical oncology