Osteoporosis - overview
Osteoporosis is a disease in which bones become fragile and more likely to fracture. Usually the bone loses density, which measures the amount of calcium and minerals in the bone.
Click to download
Thin bones; Low bone density
Causes, incidence, and risk factors
Osteoporosis is the most common type of bone disease.
Because of osteoporosis about half of all women over the age of 50 will have a fracture of the hip, wrist, or vertebra (bone of the spine) during their lifetime.
Bone is living tissue. Existing bone is constantly being replaced by new bone. Osteoporosis occurs when the body fails to form enough new bone, when too much existing bone is reabsorbed by the body, or both.
Calcium is one of the important minerals needed for bones to form. If you do not get enough calcium and vitamin D, or your body does not absorb enough calcium from your diet, your bones may become brittle and more likely to fracture.
Sometimes bone loss occurs without any cause. Caucasian women are more likely to have bone loss. Sometimes the tendency to have bone loss and thin bones is passed down through families.
A drop in estrogen in women at the time of menopause
and a drop in testosterone in men is a leading cause of bone loss. Other causes of bone loss
Other risk factors include:
There are no symptoms in the early stages of osteoporosis. Many times, people will have a fracture before learning that they have the disease.
Pain almost anywhere in the spine can be caused by fractures of the bones of the spine. These are called compression fractures
. They often occur without an injury. The pain occurs suddenly or slowly over time.
There can be a loss of height (as much as 6 inches) over time. A stooped posture or kyphosis
(also called a dowager's hump) may develop.
Exams and tests
Bone mineral density testing
(most often with a DEXA scan) measures your bone mineral density. Your health care provider uses this test to:
- Diagnose bone loss and osteoporosis
- Predict your risk of future bone fractures
- See how well osteoporosis medicine is working
A spine or hip x-ray
may show fracture or collapse of the spinal bones. However, simple x-rays of other bones are not very accurate in predicting whether you are likely to have osteoporosis.
You may need other blood and urine tests if your osteoporosis is thought to be due to a medical condition, rather than simply the usual bone loss seen with older age.
Treatment for osteoporosis may involve:
Medicines are used to strengthen bones when:
- Osteoporosis has been diagnosed by a bone density study
, whether or not you have a fracture.
- A bone fracture has occurred and a bone density test shows that you have thin bones, but not osteoporosis.
Medicines used to treat osteoporosis
- Bisphosphonates (the main drugs used to prevent and treat osteoporosis in postmenopausal women)
- Estrogens, teriparatide, raloxifene, and calcitonin
Exercise plays a key role in preserving bone density
in older adults. Some of the exercises recommended to reduce your chance of a fracture include:
- Weight-bearing exercises -- walking, jogging, playing tennis, dancing
- Free weights, weight machines, stretch bands
- Balance exercises -- tai chi, yoga
- Rowing machines
Avoid any exercise that presents a risk of falling. Also, do not do high-impact exercises that can cause fractures in older adults.
Your body needs calcium and vitamin D to keep your bones strong. Vitamin D helps your body absorb calcium
- Adults under age 50 should have 1,000 mg of calcium and 400 - 800 IU of vitamin D daily.
- Women ages 51 to 70 should have 1,200 mg of calcium and 400 - 800 IU of vitamin D a day; men ages 51 to 70 need 1,000 mg of calcium and 400 - 800 IU of vitamin D a day.
- Adults over age 70 should get 1,200 mg of calcium and 800 IU of vitamin D daily.
- Your doctor may recommend a calcium supplement
- Follow a diet that provides the proper amount of calcium and vitamin D
Stop unhealthy habits:
Quit smoking, if you smoke.
Limit your alcohol intake. Too much alcohol can damage your bones. This puts you at risk of falling and breaking a bone.
It is important to prevent falls. The following are suggestions on how to do this:
Surgery to treat severe, disabling pain from spinal fractures due to osteoporosis include:
Medicines to treat osteoporosis can help prevent future fractures. But spine bones that have already collapsed cannot be reversed.
Osteoporosis can cause a person to become disabled from weakened bones. Hip fractures are one of the main reasons people are admitted to nursing homes.
Calcium is important for building and maintaining healthy bone. Vitamin D is also needed because it helps your body absorb calcium. Following a healthy, well-balanced diet can help you get these and other important nutrients.
Other tips for prevention:
Medicines can prevent osteoporosis. Your doctor can tell you if any are right for you.
Lewiecki EM. In the clinic. Osteoporosis. Ann Intern Med. 2011;155(1):ITC1-1-15;quiz ITC1-16.
National Osteoporosis Foundation. Clinician's Guide to Prevention and Treatment of Osteoporosis. Washington, DC: National Osteoporosis Foundation; 2010.
North American Menopause Society. Management of osteoporosis in postmenopausal women: 2010 position statement of The North American Menopause Society. Menopause. 2010 Jan-Feb;17(1):25-54.
Park-Wyllie LY, Mamdani MM, Juurlink DN, Hawker GA, Gunraj N, Austin PC, et al. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA. 2011;305(8):783-789.
C. Benjamin Ma, MD, Assistant Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.