June 28, 2012
Elia Beniash, PhD
Dr. Elia Beniash is an associate professor at the University of Pittsburgh School of Dental Medicine, Department of Oral Biology. Dr. Beniash discusses his research in biogenic mineralized materials - such as those found in bones and teeth - as well as dentino-enamel interface.
March 30, 2012
J. Peter Rubin, MD
Dr. Rubin is the Chief of the Division of Plastic and Reconstructive Surgery and Associate Professor at the University of Pittsburgh. Dr. Rubin discusses his upcoming clinical trials in facial and breast reconstruction.
|February 29, 2012|
Adam Feinberg, PhD
Rachelle Palchesko, PhD
Dr. Adam Feinberg is the principal investigator of the Regenerative Biomaterials and Therapeutics Group at Carnegie Mellon University. Dr. Palchesko is a Postdoctoral Research Fellow in the group. Drs. Feinberg and Palchesko discuss the development of basement membranes and the regeneration of corneal endothelium.
|December 19, 2011 |
Philip LeDuc, PhD
Dr. Philip LeDuc is a professor of Mechanical Engineering at Carnegie Mellon University, with courtesy appointments in Biological Sciences, Biomedical Engineering, and Computational Biology. Dr. LeDuc discusses the role mechanical engineering plays in regenerative medicine as well as his project to make vegetables more palatable for malnourished infants and children.
|October 20, 2011 |
Stephen Badylak, DVM, PhD, MD
Stephen Badylak, DVM, PhD, MD, is a professor in the Department of Surgery, a deputy director of the McGowan Institute for Regenerative Medicine, and director of the Center for Pre-Clinical Tissue Engineering within the Institute. He discusses his pioneering research in whole organ engineering.
July 8, 2011
Fabrisia Ambrosio, PhD, MPT
Dr. Ambrosio is an assistant professor in the Department of Physical Medicine and Rehabilitation at the University of Pittsburgh. She is also the co-director of the Clinical Translation/Rehabilitation Lab of the Stem Cell Research Center. Dr. Ambrosio discusses the upcoming symposium that aims to unite regenerative medicine and physical therapy.
|June 13, 2011 |
Eric Lagasse, PharmD, PhD
Dr. Lagasse is an associate professor in the Department of Pathology and the director of the Cancer Stem Cell Center, a joint venture between the McGowan Institute for Regenerative Medicine and the University of Pittsburgh Cancer Institute. Dr. Lagasse provides an update on his research in cell-based therapy for liver disease, including the recent success his lab has had in generating “mini livers” in the lymph nodes
|May 24, 2011|
Cameron Riviere, PhD
Dr. Riviere is an Associate Research Professor in the Robotics Institute at Carnegie Mellon University. He is also an Adjunct Associate Professor in the Department of Rehabilitation Science and Technology at the University of Pittsburgh. Dr. Riviere discusses his research in control systems and robotic devices, and the role these devices play in biomedicine, such as robotic and mechatronic devices for microsurgery and minimally invasive surgery, filtering methods for tremor and non-tremulous error, and high-precision instrumentation to track microsurgical tools.
|March 15, 2011|
Yadong Wang, PhD
Dr. Wang is an Associate Professor of Bioengineering at the University of Pittsburgh. Dr. Wang discusses his research in tissue engineering and his focus on exploring means to translate cutting-edge materials innovations into clinical benefits
|February 11, 2011 |
Prashant Kumta, PhD
Dr. Prashant Kumta is the Edward R. Weidlein Chair at the University of Pittsburgh Swanson School of Engineering and is a professor in the Departments of BioEngineering, Chemical and Petroleum Engineering, and Mechanical Engineering and Materials Science. Dr. Kumta discusses his tissue engineering research, focusing on bone regeneration.
|November 19, 2010 |
Harvey Borovetz, PhD
Dr. Borovetz and Steven Winowich discuss the early days of Ventricular Assist Devices, and Brian Williams recounts his experience as one of the pioneering patients. Dr. Borovetz is a professor and chair in the Department of Bioengineering at the University of Pittsburgh, a professor of Chemical and Petroleum Engineering, and the Robert L. Hardesty Professor in the Department of Surgery as well as the Deputy Director of Artificial Organs and Medical Devices. Mr. Winowich is the Senior Biomedical Engineer and Director of Operations at Vital Engineering
|October 28, 2010 |
Charleen Chu, MD, PhD
Dr. Charleen Chu is Professor of Pathology, Division of Neuropathology, University of Pittsburgh School of Medicine. Dr. Chu discusses her research in Parkinson’s Disease and other neurodegenerative diseases.
|September 8, 2010|
Rocky S. Tuan, PhD
Dr. Rocky Tuan is the Director of the Center for Cellular and Molecular Engineering, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine. Dr. Tuan discusses his research to regenerate and/or restore function to diseased and damaged musculoskeletal tissues.
|July 15, 2010 |
Thomas Starzl, MD, PhD
Dr. Thomas Starzl is a professor of surgery at the University of Pittsburgh and an expert in organ transplantation. He is considered by most to be the “Father of Modern Transplantation.” Dr. Starzl discusses the history of transplantation as well as the five themes he has identified within the field of transplantation.
|June 15, 2010 |
Stephen Badylak, DVM, PhD, MD
Blair Jobe, MD
Stephen Badylak, DVM, PhD, MD, is Professor in the Department of Surgery, deputy director of the McGowan Institute for Regenerative Medicine, and Director of the Center for Pre-Clinical Tissue Engineering within the Institute, and Blair Jobe, MD, is Associate Professor of surgery in the Heart, Lung and Esophageal Surgery Institute at the University of Pittsburgh and UPMC. Together they discuss the recent successful use of tissue engineering in a non-invasive surgery to treat esophageal cancer as well as the potential benefits this technology holds for the future.
|May 28, 2010 |
W. P. Andrew Lee, MD
Dr. W. P. Andrew Lee is the former chief of the Division of Plastic Surgery at the University of Pittsburgh and the former director of the Hand Surgery Fellowship in the School of Medicine. Dr. Lee discusses the successful hand transplants recently performed by him as well as what he envisions for the future.
|February 26, 2010 |
Johnny Huard, PhD
Dr. Johnny Huard is the Henry J. Mankin Endowed Chair in Orthopaedic Surgery Research, the director of the Stem Cell Research Center, and the deputy director for cellular therapy at the McGowan Institute for Regenerative Medicine. Dr. Huard discusses adult stem cell research and the potential it has to provide future treatments for damaged or diseased tissues. He also reviews his research that is now matured to the point that clinical studies are underway.
|January 29, 2010|
Thomas W. Gilbert, PhD
Dr. Gilbert is an Assistant Professor in the Departments of Surgery and Bioengineering at the University of Pittsburgh. His research interest are focused on the remodeling of biologic scaffolds for tissue-engineering based treatments, particularly relating to role of mechanical loading in the remodeling process.
He has directed and participated in pre-clinical studies relevant to orthopaedics, cardiac, and gastrointestinal applications. He discusses his current research programs targeting tracheal reconstruction (with a particular focus on epithelialization and mechanical integrity of the graft) and tissue engineering approaches to pediatric congenital heart defects.
|December 22, 2009|
Burhan Gharaibeh, PhD
Dr. Gharaibeh is a Research Assistant Professor at the Stem Cell Research Center in the Department of Orthopaedic Surgery, University of Pittsburgh. Dr. Gharaibeh discusses muscle derived stem cells and how to use these stem cells to regenerate and repair injured skeletal muscles.
|November 30, 2009|
Ellen Gawalt, PhD
Dr. Gawalt is an Assistant Professor in the Department of Chemistry and Biochemistry at Duquesne University. She is also the Chair of the Graduate Admissions and Recruitment and a member of the NSF-REU Advisory Board. Dr. Gawalt discusses her research in controlling interfacial regions through chemical modifications by using biomaterials and biofouling.
|November 17, 2009|
Lorenzo Soletti, PhD
Dr. Soletti is the Director of Technology Development at Neograft Technologies, Inc. Dr. Soletti discusses technologies currently used in treating cardiovascular disease as well as a new technology called Angioshield that he and his colleagues at Neograft Technologies are developing.
|September 16, 2009|
Robert Bowser, PhD
Dr. Robert Bowser is the Director of the ALS Research for the Pittsburgh Institute for Neurodegenerative Diseases and at the Center for ALS Research at the University of Pittsburgh. He is also the Director of the ALS Tissue Bank where he helps to create the largest such tissue repository in the country. Dr. Bowser discusses the state of neurodegenerative diseases, such as ALS and Alzheimer’s, as well as the unique challenges they present to researchers.
|August 27, 2009 |
Major General Gale Pollock
Major General Gale Pollock is the executive director of the Louis J. Fox Center for Vision Restoration, a division of the UPMC Eye Center. Major General Pollock is with Corporal Mike Jernigan, a medically retired marine who lost both eyes in Iraq. They discuss the BrainPort vision system, which is currently being used by Corporal Jernigan, as well as its future.
|August 20, 2009 |
Bryan Tillman, MD, PhD
Dr. Bryan Tillman is an assistant professor in the Division of Vascular Surgery at the University of Pittsburgh Medicine Center as well as a practicing clinician. Dr. Tillman discusses the applications of tissue engineering to construct replacement vessels for patients with peripheral vascular disease.
|July 24, 2009 |
Mr. Patrick Cantini, Director of Scientific Collaborations at the McGowan Institute’s Center for Industry Relations, discusses the importance and the process of establishing partnerships between the McGowan Institute and commercial enterprises and how this aids the transition from the laboratory studies to medical practice.
|July 16, 2009 |
Robert Kormos, MD
Robert Kormos, MD, Director of the Artificial Heart Program, and Co-Director of Heart Transplantation at the University of Pittsburgh Medical Center, is with a former patient, Erika Haas. They discuss Erika’s experience with a Ventricular Assist Device (VAD) and how it was used as a bridge to recovery.
|May 26, 2009|
Simon Watkins, PhD
Donna Beer Stolz, PhD
Drs. Simon Watkins and Donna Beer Stolz discuss the many resources available at the Center for Biologic Imaging and the work that is done there. Dr. Watkins is the Founder and Director of the Center for Biologic Imaging at the University of Pittsburgh, and Dr. Stolz is the Assistant Director at the Center.
|April 22, 2009|
Eric Beckman, PhD
Eric Beckman, PhD, is a professor of chemical engineering at the University of Pittsburgh and the co-founder of Cohera Medical, Inc. Dr. Beckman discusses the technology that is being developed at Cohera Medical, Inc. as well as the difficulties faced when starting a small company.
|March 31, 2009 |
Peter Wearden, MD, PhD
Joel Gradowski, MD
Peter Wearden, MD, PhD, is an Assistant Professor, Pediatric Cardiac Surgery; Director Pediatric Mechanical Cardiopulmonary Support at the UPMC Children's Hospital of Pittsburgh; and a faculty member at the McGowan Institute for Regenerative Medicine. Joining Dr. Wearden is Dr. Joel Gradowski and Cindy Gradowski, who together discuss their son’s recent cardiac treatment and recovery through the use of a ventricular assist device.
|January 23, 2009|
Major General (ret.) Gale S. Pollock
Major General (ret.) Gale S. Pollock is the executive director of the nation’s first Center for Ocular Regeneration and Vision Restoration (CORVR), a division of the UPMC eye center. Major General Pollock discusses her goals for CORVR as well as current studies being done to improve quality of life for those with eye injuries and blindness.
|January 2, 2009|
Sanjeev G. Shroff, PhD
Sanjeev G. Shroff, PhD, is the Associate Chair of the Department of Bioengineering at the University of Pittsburgh; Professor and Gerald McGinnis Chair in Bioengineering; Professor of Medicine; and Senior Investigator, Magee-Women’s Research Institute. Dr. Shroff shares highlights of his scientific studies on vascular stiffness and cardiovascular function as well as large-scale mathematical simulations of biological systems for research, education, and engineering design.
|December 15, 2008|
John Pollock, PhD
Dr. John Pollock is Associate Professor-Bayer School of Natural Sciences and Environment, Duquesne University. Dr. Pollock shares highlights of his scientific studies on the mechanisms of pain generation and possible techniques for improved pain management. He also describes the videos that he and his team produce to educate the general public and students on tissue engineering and regenerative medicine.
|December 2, 2008|
David Whitcomb, MD, PhD
Dr. David Whitcomb, Professor of Medicine, Cell Biology and Physiology, and Human Genetics at the University of Pittsburgh, discusses research that is pioneering alternative diagnosis and treatment for disorders of the pancreas, liver, and the intestine. Dr. Whitcomb is also the Chief of the Division of Gastroenterology, Hepatology, and Nutrition, as well as the founder and Director of the Center for Genomic Sciences.
|November 20, 2008|
Vera Donnenberg, PhD
Dr. Vera Donnenberg is an Assistant Professor of Surgery and Pharmaceutical Science at the University of Pittsburgh. Dr. Donnenberg’s research focuses on the persistent problem in cancer treatment which is cancer recurrence after an apparently successful therapy. Cancer recurrence is mediated by a dormant and protected cancer stem/progenitor like cell. Her lab is focused on approaches that can be translated into and understanding the biologic basis for treatment failure and identifying new immunological therapeutic targets. She introduces the concept of a cancer vaccine to address these needs.
|September 15, 2008|
Steven Little, PhD
Dr. Steven Little is an Assistant Professor and Bicentennial Alumni Faculty Fellow, Departments of Chemical Engineering, Bioengineering, Immunology, and Medicine at the University of Pittsburgh. Dr. Little’s focus is on the delivery of genetic vaccines with special emphasis on non-viral, particulate formulations. His current interests include controlled delivery for tissue engineering, immunotherapeutics, and biomimetic materials.
|September 4, 2008|
Newell Washburn, PhD
Dr. Newell Washburn is an Assistant Professor in the Departments of Chemistry and Biomedical Engineering at Carnegie Mellon University. His primary research interests include wound healing and bone tissue engineering though the use of biomaterials. Dr. Washburn discusses his current studies and shares his vision on the application of emerging technologies in these areas for clinical applications.
|July 29, 2008|
Joel Schuman, MD
Dr. Joel Schuman is the Eye and Ear Foundation Professor and Chairman of Department of Ophthalmology and the director of the UPMC Eye Center. Dr. Schuman is considered to be one of the nation’s leading authorities on the treatment of glaucoma. He discusses diagnostic imaging and describes a new initiative via the Center for Ocular Regeneration and Vision Restoration.
|June 6, 2008|
Jörg C. Gerlach, MD, PhD
Dr. Joerg Gerlach discusses his work on the development of tools such as bioreactors for the expansion of cells so that sufficient cells are available for cell-based therapies. Areas of focus include the pancreas and the liver. He also explores the development of “cell factories” for the production of cells from a patient’s bone marrow. Another of Dr. Gerlach’s interests is cell-based burn therapy, which he describes.
|April 29, 2008|
Kacey Marra, PhD
Dr. Kacey Marra discusses her research focused on the use of adipose-derived stem cells for the regeneration of nerve, bone, adipose, and cartilage. The lab uses adipose-derived stem cells for these bioengineering applications. Also, Dr. Marra discusses her strong commitment to mentoring women and minorities in the career opportunities that are available in science and medicine.
|March 24, 2008|
Mr. Steve Winowich, Director of Clinical Bioengineering with the Artificial Heart Program at the University of Pittsburgh Medical Center (UPMC), describes a unique partnership between the clinical staff and a team of bioengineers and nurses who are a key component of a very successful program that provides mechanical circulatory support to patients that are waiting for a heart transplant. Supplemental circulatory support has been traditionally used as a bridge to a transplant, but there are also cases where the circulatory support has also been used as a bridge to recovery.
February 15, 2008
Phil Campbell, PhD
Dr. Phil Campbell’s research is focused on the development of “tool sets” that will be resources for regenerative medicine research and clinical therapies. In the podcast he discusses his work on methodologies and systems that will be required for cell expansion on a commercial vs. a research basis, and how his research is addressing those needs.
He also shares some insight into the use of inkjet printing technologies to print tissue engineered constructs using “bio-inks” vs. the traditional inks used in such printers. These tool sets are proving to be a significant resource in the study of cell growth on tissue engineered constructs. Finally, Dr. Campbell discusses his strong commitment to science-based education: from elementary students to senior citizens.
|February 1, 2008|
Alan Wells, MD, DMS
Dr. Alan Wells discusses his pioneering studies on tumor biology and wound healing. He shares insight into the basic science and to future clinical applications of his research. One of his interests is in the development of custom therapies, patient-by-patient, for certain illnesses, such as cancer.
|January 10, 2008|
Eric Lagasse, PharmD, PhD
Dr. Eric Lagasse discusses his pioneering research on the use of stem cells for liver therapy. He also describes his research on the identification of cancer stem cells, and possible alternative cancer therapies if the hypothesis is affirmed that cancer stem cells are the source of the tumors and the reason for metastasis.
|December 24, 2007|
Peter Wearden, MD, PhD
Dr. Peter Wearden discusses his pioneering clinical initiatives in pediatric cardiac care as well as his collaborative research in the development and assessment of pediatric mechanical circulatory support systems. He also shares his vision for the future with new procedures that could dramatically affect the treatments for children with cardiac afflictions.
|November 27, 2007|
Jennifer Braemar Ogilvie , MD
Dr. Jennifer Ogilvie discusses her clinical focus, endocrine surgery, and her current regenerative medicine research interests that focus on the development of tissue-engineered endocrine organs, in particular bioengineered parathyroid and adrenal glands. Also, her initial studies on the development of a tumor vaccine and her strong commitment to student mentoring are discussed.
|October 17, 2007|
David Vorp, PhD
Dr. David Vorp discusses the assessment of mechanical factors in the genesis and progression of vascular diseases such as arterial aneurysms, atherosclerosis, vascular graft failure, and the development of tissue-engineered blood vessels. He also describes some new initiatives, such as the use of tissue engineering to treat urethral dysfunction.
|August 1, 2007|
Alejandro Nieponice, MD
Dr. Alejandro Nieponice discusses the Clinical Translation Unit within the operative room at the Austral University Hospital, providing full cell culture capabilities to facilitate clinical translation of cell-based technologies.
June 28, 2007
David G. Baer, PhD
Dr. David Baer is the Director of the Research Office at the Institute of Surgical Research in San Antonio, Texas. In the podcast, Dr. Baer discusses:
- Mission of the Army includes operational medicine; aka sports medicine in the civilian world
- Institute’s Focus on combat casualty care and traumatic injury
- Interest in Regenerative Medicine to address severe injuries
- The new medical challenges from the current conflict
- The broad scope of the Institute from basic science to clinical studies
- Training and career opportunities at ISR
|June 3, 2007|
Michael Sacks, PhD
Dr. Michael Sacks discusses his work on the characterization of cardiac tissue and the various alternatives—now and in the future—for the repair of heart valves.
|May 18, 2007|
Bruno Peault, PhD
Dr. Bruno Peault discusses the status of his emerging results on the identification, characterization, and application of adult stem cells for therapeutic applications.
|April 30, 2007|
Rory Cooper, PhD
Dr. Rory Cooper is the Chair and Distinguished University Professor, Department of Rehabilitation Science and Technology, University of Pittsburgh. In this podcast, he highlights some of the promising initiates emerging from his laboratories and from the Quality of Life Technology Center.
|March 27, 2007|
Stephen Badylak DVM, PhD, MD
Today, Dr. Badylak describes the work of his lab and collaboration with other colleagues to use tissue engineering to regenerate a diseased or damaged esophagus and technology that may lead to the regeneration of damaged or severed digits or limbs.
|February 15, 2007|
Michael Chancellor, MD
Dr. Michael Chancellor is a Professor of Urology at the University of Pittsburgh as well as a practicing OBGYN.
|February 13, 2007|
Michael Chancellor, MD
Dr. Michael Chancellor discusses an alternative approach to the treatment of adult urinary incontinence.
|January 15, 2007 |
Yoram Vodovotz , PhD
Dr. Yoram Vodovotz discusses the research that he and his colleagues are pursuing to model inflammatory responses in the body. They have used these models to successfully predict the outcomes of drug trials.
December 28, 2006
Alan J. Russell, PhD
Dr. Alan Russell, director of the McGowan Institute for Regenerative Medicine, addresses:
- The history of the emergence of regenerative medicine, from over-hyped laboratory results, to failed medical devices, to successful clinical applications
- The role of governments in the advancing the state-of- the-art and the clinical use of regenerative medicine technologies
- Initiatives to assist soldiers (and, ultimately, the civilian population) who have suffered massive loss of tissue due to trauma
- The status of the professional society that serves the scientists who are developing regenerative medicine technologies
|October 27, 2006 |
William R. Wagner, PhD
Dr. William Wagner is working to reconstruct damaged arteries and veins with scaffolds, and is leading a team that is developing a tissue engineered cardiac patch that could help to strengthen heart muscle that has been damaged by a heart attack. Dr. Wagner also will tell us about his work to improve the interface between artificial devices and the body’s tissues, and about a new imaging technique his lab is working on that could help physicians view whether a transplanted heart has been rejected without performing a biopsy.
|October 11, 2006|
Robert Kormos, MD
In this podcast, Dr. Kormos discusses the evolution of his program and the clinical use of artificial hearts, and he tells us how regenerative medicine will continue to transform the treatment of heart failure.
|September 29, 2006 |
Harvey S. Borovetz, PhD
In this interview, Dr. Borovetz provides a retrospective look at the initial days of what has become a relatively routine clinical procedure to support a weakened heart with a ventricular assist device until a heart transplant can be implemented. Dr. Borovetz shares the progress that has been made in the engineering as well as the clinical procedures. He also provides a glimpse at the future, sharing his vision on the emerging technology development that he is leading to provide equivalent cardiac care for infants and children.
|August 31, 2006 |
William Federspiel, PhD
Dr. William Federspiel is developing devices that do some of the lungs’ critical work of adding oxygen to blood and removing carbon dioxide.
|May 15, 2006 |
Savio L-Y. Woo, PhD, DSc
Dr. Savio Woo and his team at the Muscular Skeletal Research Center (MSRC) are the important partners to the surgeons, developing a fundamental understanding of the function of the ACL and the other components of the knee.
|February 14, 2006|
Stephen Badylak, DVM, PhD, MD
Dr. Stephen Badylak is a Professor in the Department of Surgery, a deputy director of the McGowan Institute for Regenerative Medicine, and Director of the Center for Pre-Clinical Tissue Engineering within the Institute. He discusses extracellular matrix and its many uses.
December 15, 2005
Alan J. Russell, PhD
Dr. Alan Russell is the Director of the McGowan Institute for Regenerative Medicine. In this inaugural podcast, he discusses the current state of regenerative medicine and where it is headed in the future.